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APHA Scientific > Services > Biological Reagents > Transmissible Spongiform Encephalopathy (TSE)

Transmissible Spongiform Encephalopathy (TSE) Tissue Collection

APHA is able to offer a unique selection of TSE reference tissues in support of research groups working towards the development and validation of TSE diagnostic tests.

    Our service includes the provision of premium material from the TSE Biological archive generated and maintained by APHA.

    The Archive receives and stores a range of animal tissues collected from both UK field cases and experimental programmes. It is the most extensive collection of TSE tissues worldwide and operates to a quality management system compliant with ISO 9001:2015.

    The provenance of samples held in the TSE archive has been determined by the World Organisation for Animal Health (WOAH) reference laboratory for TSE, based at APHA. Many positive cases have been confirmed with immunohistochemistry and western-blot methodology, performed under ISO 17025.

    For more information about the Biological Archive please visit the TSE International Reference Laboratory website TSEglobalNet at: https://science.vla.gov.uk/tseglobalnet/

    APHA TSE Archive Collection – Tissues available for sale*

    SpeciesTissue TypeAnimal Disease StatusPrice per gram of frozen tissue or wax block (£)
    BovineBrain (incl brainstem)Classical BSE positive1,000
    OvineBrain (incl stem)Classical Scrapie positive750
    OvineLymph nodeClassical Scrapie positive1,000
    OvineBrain (Incl brainstem & cerebellum)**Atypical Scrapie positive3,000
    OvineBrain (incl brainstem)BSE positive2,000
    OvineLymph nodeBSE positive2,000

    *Excluding VAT and P&P
    **We aim to distribute wax blocks were at least the cerebellum is positive; wax blocks containing positive obex and cerebellum are subjected to availability

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