Products and Services
Close menu
We value your input!
Share your thoughts on our new website
Contact Us

APHA Scientific is supported by a team of business development managers, customer service advisors, experienced scientists and reagent production specialists.

The APHA Scientific Customer Services Team are available to discuss your requirements. Please contact:

For further APHA contacts, please see the APHA contact page on GOV.UK.

Commercial Enquiries
Biological Reagents
Laboratory Testing
VETQAS Proficiency Testing
Close menu

This site uses cookies to store information on your computer or device…

Accept all

Accept all

…or choose your personal preferences using the information and options below:

These cookies are used for a variety of reasons, from anonymously tracking your activity, to offering additional functionality and marketing. We recommend accepting all cookies to offer the best user experience, but you can choose to block specific types of cookies using the settings below if you prefer.

Access our full privacy and cookies policy

We use analytics cookies to anonymously track your user journey and interactions with our website. This information is used to help us understand the user experience and to work towards improving the website and the content we publish.

We use these cookies to ensure you have the best user experience possible on our site and so that we do not serve you the same messages multiple times in a session.

We use these cookies to measure the effectiveness of our marketing, to offer you the most relevant insights and information and to tailor our communications with you.

Close
Search
Close search
APHA Scientific > Services > Biological Reagents > Brucellosis > Synthetic Brucella Antigens

Synthetic Brucella Antigens

APHA Scientific has developed a portfolio of synthetic oligosaccharide antigens for use in Brucella serological assays. Developed in collaboration with the University of Alberta, these chemically defined antigens have been designed to replicate diagnostically important structures found on Brucella bacteria while offering a safe alternative to conventionally produced biological antigens.

    Innovation in Brucella Diagnostics

    The synthetic antigen portfolio builds upon APHA’s expertise in brucellosis research, surveillance and diagnostic testing. By using precise synthetic chemistry, these antigens deliver consistent composition and performance, helping to overcome some of the limitations associated with traditional antigen production.

    APHA is internationally recognised for its expertise in brucellosis research and diagnostics. Our synthetic antigen portfolio combines leading scientific research with practical diagnostic knowledge, delivering innovative tools to support animal health laboratories, researchers and diagnostic developers worldwide.

    Available Synthetic Antigens

    M Disaccharide: Designed to maximise diagnostic specificity while reducing false positive serological reactions.

    M Tetrasaccharide: A synthetic antigen that has demonstrated strong diagnostic performance, supporting both sensitivity and specificity.

    tA Trisaccharide: Provides broad antibody recognition and may be used independently or in combination with M antigens to enhance diagnostic coverage.

    Synthetic Brucella Antigens are not currently available as standard catalogue products. For information on availability, collaborative opportunities, research applications or commercial licensing, please contact the APHA Scientific team.

    Why switch to synthetic antigens?

    Conventional Brucella serology relies on biologically derived antigens. These synthetic antigens provide a precisely defined safe (non-infectious) alternative, designed to improve specificity, reduce false positive reactions and deliver consistent batch-to-batch performance, while supporting future advances in diagnostic testing.

    WOAH-recognised approach:

    The use of synthetic antigens for Brucella serology is recognised within the WOAH Manual for Terrestrial Animals (Chapter 3.1.4 Brucellosis)

    Key features

    • Improved specificity with reduced false positive serological reactions.
    • Synthetic, chemically defined antigens for consistent batch-to-batch performance.
    • Safe synthetic alternative to conventional pathogen-derived antigen production.
    • Described within the WOAH Manual for Brucellosis.
    • Potential application in future DIVA (Differentiate Infected from Vaccinated Animals) testing strategies.
    • Effective for multiple livestock species including cattle, sheep, goats and pigs
    Enquire About AvailabilitySend us a message through our enquiry form.
    • Click ‘Enquiry Basket’ button
    • Select Biological Reagents
    • Add your enquiry information
    • Submit enquiry

    Enquiry Basket

    Latest News

    Keep up to date with the latest news and information from APHA Scientific

    View all news

    Meet APHA Scientific at EAVLD 2026

    APHA Scientific will be attending the EAVLD 2026 Congress in Athens, connecting with veterinary diagnosticians and laboratory professionals from across Europe. Visit our team to learn more about our proficiency testing schemes, diagnostic reagents and quality assurance solutions for veterinary laboratories.

    Read the article Read the article

    World Buiatrics Congress 2026

    The World Buiatrics Congress 2026 provides a global platform for sharing knowledge on cattle health and production. APHA Scientific will be showcasing products and expertise that support the diagnosis and control of important bovine diseases.

    Read the article Read the article

    Supporting laboratory validation with pathology control blocks

    FFPE control materials are now available to support training, quality assurance and specialised laboratory testing.

    Read the article Read the article

    APHA Science in Partnership Conference

    APHA Scientific will be attending the APHA Science in Partnership Conference in York this November. The event brings together stakeholders from across science, policy and industry to explore collaboration, innovation and shared challenges.

    Read the article Read the article

    New Salmonella Serotyping Antisera

    Our Salmonella serotyping antisera portfolio is now available, supporting confirmation, serogrouping and flagellar characterisation in veterinary diagnostic laboratories.

    Read the article Read the article

    APHA Scientific to contribute expertise at chemical and biological risk management event

    APHA will join the Star Ecotronics training event APHA, including a roundtable session for direct engagement with VETQAS customers.

    Read the article Read the article

    2026–2027 Biological Reagent Price List

    New pricing for our biological reagents is now available, with updated costs applying from 1 April 2026.

    Read the article Read the article

    AHNTI EU 2026 in London

    Meet our Business Development team at AHNTI EU 2026, where 850+ leaders are shaping the future of animal health.

    Read the article Read the article