Challenge Models

The Agency holds a great variety of antigens for which it could set up in vivo models and study both pathogenesis and vaccines. APHA Scientific also offers a wide range of animal disease challenge models for testing the efficacy of experimental vaccines.

The stock of our challenge models can fluctuate. Please contact us for further details as availability can be limited and subject to the relevant licences. New models can be developed to meet the needs of our customers.

Bacteria	Species	Model	Key
Campylobacter	Chickens / Turkeys	Colonisation / Probiotics	C
Campylobacter	Chickens	Challenge	B, C
Clostridium perfringens – Necrotic Enteritis	Avian	Challenge	A
Clostridium perfringens – Necrotic Enteritis	Chickens	Colonisation / Probiotics
Enterococci	Chickens	Challenge	A, C
Escherichia coli	Avians / Pigs / Cattle / Sheep	Challenge	A, C
Escherichia coli	Chickens	Challenge	B, C
Escherichia coli	Wax Moth / Waxworm	Virulence / Colonisation	C
Mycobacterium bovis	Cattle	Challenge
Salmonella Enteritidis	Chickens	Challenge	B
Salmonella Typhimurium	Chickens	Challenge	B
Salmonella	Avian / Pigs	Challenge	A
Salmonella	Wax Moth / Waxworm	Virulence / Colonisation

Key

A	Colonisation / Persistance / Pathogenesis
B	Colonisation plus use of antimicrobials
C	May require new HO license, advance notice need

Virus	Species	Model
African Swine Fever	Pigs	Challenge
Avian Influenza	Chickens / Pigs / Ferrets / Turkeys / Ducks	Challenge
Bovine Viral Diarrhoea	Cattle	Challenge
Classical Swine Fever	Pigs	Challenge
Infectious Bursal Disease	Chickens	Challenge
Infectious Bronchitis	Poultry	Disease
Newcastle disease	Chickens / Turkey / Game Birds	Challenge
Porcine Reproductive and Respiratory Syndrome	Pigs	Challenge
Schmallenberg	Sheep	Challenge
Swine Influenza	Pigs / Ferrets	Challenge

Our news

Keep up to date with the latest news and information from APHA Scientific

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APHA Science in Partnership Conference

APHA Scientific will be attending the APHA Science in Partnership Conference in York this November. The event brings together stakeholders from across science, policy and industry to explore collaboration, innovation and shared challenges.

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New Salmonella Serotyping Antisera

Our Salmonella serotyping antisera portfolio is now available, supporting confirmation, serogrouping and flagellar characterisation in veterinary diagnostic laboratories.

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APHA Scientific to contribute expertise at chemical and biological risk management event

APHA will join the Star Ecotronics training event APHA, including a roundtable session for direct engagement with VETQAS customers.

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2026–2027 Biological Reagent Price List

New pricing for our biological reagents is now available, with updated costs applying from 1 April 2026.

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AHNTI EU 2026 in London

Meet our Business Development team at AHNTI EU 2026, where 850+ leaders are shaping the future of animal health.

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Order Your VETQAS 2026–27 Proficiency Testing Schemes

We’re pleased to announce the release of our updated price lists for the 2026–2027 contract year.

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Visit APHA Scientific at AAVLD – Booth 305

We’re exhibiting at the AAVLD/USAHA Annual Meeting and ready to connect—stop by Booth 305 to say hello!

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APHA Scientific at WVPAC 2025

Our team had a fantastic time at WVPAC 2025, connecting with poultry health professionals from around the world and sharing insights across the industry.

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