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APHA Scientific > Services > Vaccine Development > Challenge Models

Challenge Models

The Agency holds a great variety of antigens for which it could set up in vivo models and study both pathogenesis and vaccines. APHA Scientific also offers a wide range of animal disease challenge models for testing the efficacy of experimental vaccines.

The stock of our challenge models can fluctuate. Please contact us for further details as availability can be limited and subject to the relevant licences. New models can be developed to meet the needs of our customers.

    BacteriaSpeciesModelKey
    CampylobacterChickens / TurkeysColonisation / ProbioticsC
    CampylobacterChickensChallengeB, C
    Clostridium perfringens – Necrotic EnteritisAvianChallengeA
    Clostridium perfringens – Necrotic EnteritisChickensColonisation / Probiotics
    EnterococciChickensChallengeA, C
    Escherichia coliAvians / Pigs / Cattle / SheepChallengeA, C
    Escherichia coliChickensChallengeB, C
    Escherichia coliWax Moth / WaxwormVirulence / ColonisationC
    Mycobacterium bovisCattleChallenge
    Salmonella EnteritidisChickensChallengeB
    Salmonella TyphimuriumChickensChallengeB
    SalmonellaAvian / PigsChallengeA
    SalmonellaWax Moth / WaxwormVirulence / Colonisation

    Key

    AColonisation / Persistance / Pathogenesis
    BColonisation plus use of antimicrobials
    CMay require new HO license, advance notice need
    VirusSpeciesModel
    African Swine FeverPigsChallenge
    Avian InfluenzaChickens / Pigs / Ferrets / Turkeys / DucksChallenge
    Bovine Viral DiarrhoeaCattleChallenge
    Classical Swine FeverPigsChallenge
    Infectious Bursal DiseaseChickensChallenge
    Infectious BronchitisPoultryDisease
    Newcastle diseaseChickens / Turkey / Game BirdsChallenge
    Porcine Reproductive and Respiratory SyndromePigsChallenge
    SchmallenbergSheepChallenge
    Swine InfluenzaPigs / FerretsChallenge

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