Challenge Models

The Agency holds a great variety of antigens for which it could set up in vivo models and study both pathogenesis and vaccines. APHA Scientific also offers a wide range of animal disease challenge models for testing the efficacy of experimental vaccines.

The stock of our challenge models can fluctuate. Please contact us for further details as availability can be limited and subject to the relevant licences. New models can be developed to meet the needs of our customers.

Bacteria	Species	Model	Key
Campylobacter	Chickens / Turkeys	Colonisation / Probiotics	C
Campylobacter	Chickens	Challenge	B, C
Clostridium perfringens – Necrotic Enteritis	Avian	Challenge	A
Clostridium perfringens – Necrotic Enteritis	Chickens	Colonisation / Probiotics
Enterococci	Chickens	Challenge	A, C
Escherichia coli	Avians / Pigs / Cattle / Sheep	Challenge	A, C
Escherichia coli	Chickens	Challenge	B, C
Escherichia coli	Wax Moth / Waxworm	Virulence / Colonisation	C
Mycobacterium bovis	Cattle	Challenge
Salmonella Enteritidis	Chickens	Challenge	B
Salmonella Typhimurium	Chickens	Challenge	B
Salmonella	Avian / Pigs	Challenge	A
Salmonella	Wax Moth / Waxworm	Virulence / Colonisation

Key

A	Colonisation / Persistance / Pathogenesis
B	Colonisation plus use of antimicrobials
C	May require new HO license, advance notice need

Virus	Species	Model
African Swine Fever	Pigs	Challenge
Avian Influenza	Chickens / Pigs / Ferrets / Turkeys / Ducks	Challenge
Bovine Viral Diarrhoea	Cattle	Challenge
Classical Swine Fever	Pigs	Challenge
Infectious Bursal Disease	Chickens	Challenge
Infectious Bronchitis	Poultry	Disease
Newcastle disease	Chickens / Turkey / Game Birds	Challenge
Porcine Reproductive and Respiratory Syndrome	Pigs	Challenge
Schmallenberg	Sheep	Challenge
Swine Influenza	Pigs / Ferrets	Challenge

Our news

Keep up to date with the latest news and information from APHA Scientific

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Welcome to Our New APHA Scientific Website

We’re excited to share our new and improved APHA Scientific website. This project reflects our commitment to providing a more modern, accessible, and user-friendly platform to our global commercial customer base.

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APHA Scientific at WAVLD 2025: Advancing Veterinary Diagnostics Together

We were pleased to attend the World Association of Veterinary Laboratory Diagnosticians (WAVLD) 2025 conference in Calgary, Canada, as a Silver Sponsor.

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APHA Scientific – Launch of PT-LIMS: Our New Laboratory Information Management System

We’re excited to announce the launch of PT-LIMS, our improved Proficiency Testing Laboratory Information Management System, now live for all registered customers.

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New price Lists Available for 2025–2026 Proficiency Testing Schemes & Biological Reagents

We’re pleased to announce the release of our updated price lists for the 2025–2026 contract year.

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VETQAS Terms and Conditions (T&Cs)

We want to let you know that our VETQAS T&Cs have recently been updated to reflect changes in business practices and legal requirements.

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APHA Scientific – Successful Accreditation Visit and Transition to New ISO Standard

In February, VETQAS welcomed assessors for our annual UKAS accreditation visit, a vital part of maintaining our high standards and commitment to quality.

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VETQAS Proficiency Testing – Help Us Improve with Our Customer Survey

VETQAS Proficiency Testing are always looking for ways to improve our services, and your feedback plays a crucial role in helping us achieve that goal.

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APHA Scientific attending AAVLD 2024

APHA Scientific business development team is exhibiting at the American Association of Veterinary Laboratory Diagnosticians annual meeting which takes place on October 12 – 13, 2024 at Gaylord Opryland Resort & Convention Center in Nashville, USA.

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