Challenge Models

The Agency holds a great variety of antigens for which it could set up in vivo models and study both pathogenesis and vaccines. APHA Scientific also offers a wide range of animal disease challenge models for testing the efficacy of experimental vaccines.

The stock of our challenge models can fluctuate. Please contact us for further details as availability can be limited and subject to the relevant licences. New models can be developed to meet the needs of our customers.

Bacteria	Species	Model	Key
Campylobacter	Chickens / Turkeys	Colonisation / Probiotics	C
Campylobacter	Chickens	Challenge	B, C
Clostridium perfringens – Necrotic Enteritis	Avian	Challenge	A
Clostridium perfringens – Necrotic Enteritis	Chickens	Colonisation / Probiotics
Enterococci	Chickens	Challenge	A, C
Escherichia coli	Avians / Pigs / Cattle / Sheep	Challenge	A, C
Escherichia coli	Chickens	Challenge	B, C
Escherichia coli	Wax Moth / Waxworm	Virulence / Colonisation	C
Mycobacterium bovis	Cattle	Challenge
Salmonella Enteritidis	Chickens	Challenge	B
Salmonella Typhimurium	Chickens	Challenge	B
Salmonella	Avian / Pigs	Challenge	A
Salmonella	Wax Moth / Waxworm	Virulence / Colonisation

Key

A	Colonisation / Persistance / Pathogenesis
B	Colonisation plus use of antimicrobials
C	May require new HO license, advance notice need

Virus	Species	Model
African Swine Fever	Pigs	Challenge
Avian Influenza	Chickens / Pigs / Ferrets / Turkeys / Ducks	Challenge
Bovine Viral Diarrhoea	Cattle	Challenge
Classical Swine Fever	Pigs	Challenge
Infectious Bursal Disease	Chickens	Challenge
Infectious Bronchitis	Poultry	Disease
Newcastle disease	Chickens / Turkey / Game Birds	Challenge
Porcine Reproductive and Respiratory Syndrome	Pigs	Challenge
Schmallenberg	Sheep	Challenge
Swine Influenza	Pigs / Ferrets	Challenge

Our news

Keep up to date with the latest news and information from APHA Scientific

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Visit APHA Scientific at AAVLD – Booth 305

We’re exhibiting at the AAVLD/USAHA Annual Meeting and ready to connect—stop by Booth 305 to say hello!

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APHA Scientific at WVPAC 2025

Our team had a fantastic time at WVPAC 2025, connecting with poultry health professionals from around the world and sharing insights across the industry.

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Discover More About APHA Scientific’s Work Behind the Scenes

Explore how our teams contribute to animal and public health through research, diagnostics, and innovation in our latest blog post.

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Welcome to Our New APHA Scientific Website

We’re excited to share our new and improved APHA Scientific website. This project reflects our commitment to providing a more modern, accessible, and user-friendly platform to our global commercial customer base.

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APHA Scientific at WAVLD 2025: Advancing Veterinary Diagnostics Together

We were pleased to attend the World Association of Veterinary Laboratory Diagnosticians (WAVLD) 2025 conference in Calgary, Canada, as a Silver Sponsor.

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APHA Scientific – Launch of PT-LIMS: Our New Laboratory Information Management System

We’re excited to announce the launch of PT-LIMS, our improved Proficiency Testing Laboratory Information Management System, now live for all registered customers.

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New price Lists Available for 2025–2026 Proficiency Testing Schemes & Biological Reagents

We’re pleased to announce the release of our updated price lists for the 2025–2026 contract year.

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VETQAS Terms and Conditions (T&Cs)

We want to let you know that our VETQAS T&Cs have recently been updated to reflect changes in business practices and legal requirements.

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